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A trade route is a common path of travel for those who frequently traverse between any points of barter interest. The route is considered preferable based on ease of travel. These routes exist everywhere across the planet, and they are usually organized by means of travel through space/time— via water, air, land, or other means.
Silk and Spice Routes connected various empires across Europe and Asia, including the Roman Empire and the Han Dynasty, around the 1st century. These routes connected a number of trading posts and spanned a large part of the known world. See Silk Road.
Incense Routes connected the Arab world to Europe and were largely run by Arabian traders supplying items like frankincense and myrrh.
The Amber Road connected the North Sea and Baltic Sea coasts by way of the Vistula and Dnieper rivers to Italy, Greece, Black Sea and Egypt. The Silk Road could then be reached from the Black Sea for further transporting Baltic amber.