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Skeletal muscle is a type of striated muscle, attached to the skeleton. Skeletal muscles are used to facilitate movement, by applying force to bones and joints; via contraction. They generally contract voluntarily (via nerve stimulation), although they can contract involuntarily.
Muscles have an elongated, cylindrical shape, and are multinucleated. The nuclei of these muscles are located just under the plasma membrane, which vacates the central part of the muscle fiber for myofibrils. This unique arrangement of the nuclei allows for higher efficiency. These muscles usually have one end (the "origin") attached to a relatively stationary bone, (such as the scapula) and the other end (the "insertion") is attached across a joint, to another bone (such as the humerus).
There are two types of fibers for skeletal muscles: Type I and Type II. Type I fibers appear reddish. They are good for endurance and are slow to tire because they use oxidated metabolism. Type II fibers are whitish; they are used for short bursts of speed and power, use anaerobic metabolism, and are therefore quicker to tire.
| Fibre Type | Type I fibres | Type II A fibres | Type II B fibres |
| Contraction time | Slow | Fast | Very Fast |
| Size of motor neuron | Small | Large | Very Large |
| Resistance to fatigue | High | Intermediate | Low |
| Activity Used for | Aerobic | Long term anaerobic | Short term anaerobic |
| Force production | Low | High | Very High |
| Mitochondrial density | High | High | Low |
| Capillary density | High | Intermediate | Low |
| Oxidative capacity | High | High | Low |
| Glycolytic capacity | Low | High | High |
| Major storage fuel | Triglycerides | CP, Glycogen | CP, Glycogen |
The strength of skeletal muscle is directly proportional to its cross-sectional area. The strength of a body, however, is determined by a number of biomechanical principles (the distance between muscle insertions and joints, muscle size, and so on). Muscles are normally arranged in opposition so that as one group of muscles contract, another group relaxes or expands.
Skeletal muscle cells are stimulated by acetylcholine, which is released at neuromuscular junctions by motor neurons. Once the cells are "excited", their sarcoplasmic reticulums will release ionic calcium (Ca2+), this interacts with the myofibrils and, thus, induces muscular contraction (via the sliding filament mechanism). Besides calcium, this process requires adenosine triphosphate (ATP). The ATP is produced by metabolizing creatine phosphate and glycogen, which are stored within the muscle cells; as well by metabolizing glucose and fatty acids, obtained from blood.
Each motor neuron "controls" a group of muscle cells, known as "motor units". When more strength is required, than what can be obtained from a single motor unit, more units will be stimulated; this is known as "motor unit recruitment". If more strength is required than what can be obtained from the current degree of unit contraction, the motor neurons will send additional stimuli; this causes a process of contractile summation, which increases the degree of contraction. If a muscle is maximally contracted, it is said to be in a state of tetanic contraction.
Skeletal muscles contain two types of fibers, used to produce ATP; the amount of each varies from muscle to muscle, and from person to person.
See also: cardiac muscle, Muscular system |- |align=center| Cardiac muscle - Skeletal muscle - Smooth muscle - List of muscles of the human body |}