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Spencer Horatio Walpole (1807-1898) was a British politician, three times Home Secretary under Lord Derby. His son, Spencer Walpole, was a notable historian.
| Preceded by: Sir George Grey, Bt | Home Secretary 1852 | Followed by: The Viscount Palmerston | ||
| Preceded by: Sir George Grey, Bt | Home Secretary 1858–1859 | Followed by: Sir George Grey, Bt | Home Secretary 1866–1867 | Followed by: Gathorne Hardy |