Parietal cell
Parietal cells (wall cells) are cells located in the stomach epidermis, which produce gastric acid (hydrochloric acid) to maintain the acidic environment needed by enzymes.
The disease peptic ulcer results from over-acidity in the stomach. Instead of giving antacids, medicines have been developed to inhibit the acid-releasing process of the parietal cells. The active substance omeprazole is an example of a modern proton pump inhibitor.
In achlorhydria, the parietal cells are attacked by the immune system, leading to an increase in pH and problems with digestion.
