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The megakaryocyte is a bone marrow cell that functions as a committed precursor for platelets. It is so called because on light microscopy it has many nuclei (karyo) and is exceptionally large (mega). ()
Megakaryocyte function is determined by a large number of cytokines, including thrombopoietin.
The developmental history of the megakaryocyte is: hemocytoblast -> megakaryocyte -> promegakaryocyte -> megakaryocyte
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