Giovanni di Bicci de' Medici (1360–1464)
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Cosimo de' Medici (the Elder) (1389–1464)
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Piero I de' Medici (the Gouty) (1416–1469), Lord of
Florence
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Giuliano de' Medici (1453–1478)
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Giulio de' Medici (1478–1534), Pope Clement VII
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Alessandro de' Medici (the Moor) (1511–1537), Duke of
Tuscany
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Giulio de' Medici (ca. 1533–1600)
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Giulia de' Medici (ca. 1535–?)
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Lorenzo de' Medici (the Magnificent) (1449–1492), Lord of Florence
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| | +-Lucrezia de' Medici (1470–1550)
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| | | +-Maria Salviati (1499–1543), wife of Giovanni dalle bande nere (see below)
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| | | +-Francesca Salviati
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Alessandro de' Medici (1535–1605), Pope Leo XI
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Piero II de' Medici (the Unfortunate) (1472–1503), Lord of Florence
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Lorenzo II de' Medici (1492–1519), Duke of
Urbino
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Catherine de' Medici (1519–1589), wife of
Henry II of France
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| | +-Maddalena de' Medici (1473–1528)
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Giovanni de' Medici (1475–1521), Pope Leo X
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Giuliano de' Medici (1479–1516), Duke of Nemours
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| | | +-Ippolito de' Medici (1511–1535), Cardinal
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| | +-Contessina de' Medici (?–1515), wife of Piero Ridolfi
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Giovanni de' Medici (1421–1483)
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| +-Carlo de' Medici (1430–1492)
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Lorenzo de' Medici (the Elder) (1395–1464)
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+-Pierfrancesco de' Medici (the Elder) (1430–1476)
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Lorenzo the Popolano (1463–1503), Lord of
Piombino
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| +-Pierfrancesco de' Medici (the Younger) (1487–1525)
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| +-Laudomia de' Medici (1463-?)
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| +-Lorenzino de' Medici (1514–1548) (also called Lorenzaccio)
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| +-Giuliano the Medici (ca. 1520–1588)
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| +-Maddalena de' Medici (?–1583)
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+-Giovanni the Popolano (1467–1498)
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+-Giovanni dalle Bande Nere (1498–1526)
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Cosimo I de' Medici (1519–1574), Grand duke of Tuscany
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+-Francesco I de' Medici (1541–1587), Grand duke of Tuscany
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| +-Eleanora de' Medici (1567–1611)
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Marie de' Medici (1573–1642), wife of
Henry IV of France
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| +-Antonio de' Medici (1576–1621)
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+-Isabella de' Medici (1542–1576)
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+-Giovanno de' Medici (1543–1562), bishop of
Pisa and cardinal
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+-Lucretia de' Medici (1545–1562), wife of Alfonso II d'Este, Duke of Ferrana and
Modena
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+-Ferdinando I de' Medici (1549–1609), Grand duke of Tuscany
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| +-Cosimo II de' Medici (1590–1621), Grand duke of Tuscany
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| | +-Ferdinando II de' Medici (1610–1670), Grand duke of Tuscany
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| | | +-Cosimo III de' Medici (1642–1723), Grand duke of Tuscany
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| | | +-Ferdinando III de' Medici (1663–1713)
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Anna Maria Luisa de' Medici (1667–1743)
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Gian Gastone de' Medici (1671–1737), Grand duke of Tuscany
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| | +-Giovanno Carlo de' Medici (1611–1663), Bishop of Sabina
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| | +-Margherita de' Medici (1617–1675), wife of Odoardo I Farnese, count of Parma
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| | +-Anna de' Medici (1616–1676), wife of archduke Ferdinand Karl of Austria
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| | +-Leopoldo de' Medici (1617–1675), Cardinal
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| +-Claudia de' Medici (1604–1648), wife of archduke Leopold V of Austria
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+-Pietro de' Medici (1554–1604)
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