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Karyorrhexis is the fragmentation of the nucleus of a cell undergoing programmed cell death (see Naoufal Zamzami and Guido Kroemer: "Apoptosis: Condensed matter in cell death", Nature Vol. 401 p. 127, 09 Sep. 1999 ).
It is usually preceded by pyknosis (clumping and condensation of chromatin in the nucleus).
See also:
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