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Kara Kennedy Allen was born on February 27, 1960 in Bronxville, New York. She is the only daughter of Senator Edward Kennedy and Virginia Joan Bennett.
She married Michael Allen on September 9, 1990 in Centerville, Massachusetts. They have two children: Grace Kennedy Allen, born September 19, 1994 in Washington D.C. and Max Greathouse Allen, born December 20, 1996 in Rockville, Maryland.
Kara formerly worked for Very Special Arts, a creative counterpart to Special Olympics founded by her aunt Jean. She was also formerly on the board of directors for the National Organization on Fetal Alcohol Syndrome.
In 2003, she was diagnosed with lung cancer. As of 2004, she was in remission.