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A fictional chemical substance is a chemical element, isotope, compound or mineral that exists only in works of fiction (usually fantasy or science fiction). It should be noted that no actual periodic elements end in '-ite', though many minerals have names with this suffix. Some of the materials listed below may indeed be minerals, alloys, or other such combinations instead of being pure elements, but fictional works are often vague on such distinctions. Grouping is done by what seems most likely.
Spoiler warning: Plot or ending details follow.
| Name | Source | Uses |
|---|---|---|
| Adamantium | Marvel Comics, Samurai Jack, some fantasy role-playing games | The strongest metal known in the universe of Marvel Comics. Once cast, it cannot be bent, blunted, or broken. It is used in weapons, notably Wolverine's claws and various robots. Captain America's shield is sometimes said to be Adamantium, but is actually an unknown alloy of Vibranium and iron. Adamantium was discovered by accident in an attempt to recreate the shield's metal. |
| Administratium | Joke | A well-known joke in scientific circles, a spoof on the bureaucracy of scientific establishments and on descriptions of newly discovered elements. |
| Balthorium | Dr. Strangelove | An isotope, Balthorium G, has a radioactive halflife of 93 years. It is used in a doomsday machine which will release it into the atmosphere if triggered. Not related to real-life thorium. |
| Carbonadium | Marvel Comics | A malleable form of adamantium. |
| Cavorite | H. G. Wells' The First Men in the Moon; also used in The League of Extraordinary Gentlemen | Cavorite is impervious to gravity and can shield other material from its effects. It is used to shield a craft from Earth's pull, allowing easy flight. It was named after its discoverer, Mr. Cavor, who used its levitational properties to travel to the Moon. |
| Dalekanium | Doctor Who | A metal used by the Daleks in the manufacture of extremely powerful bombs. Depleted Dalekanium is also used in their armor. |
| Dilithium | Star Trek | A reddish-orange crystal capable of moderating matter-antimatter annihilations, used in the reactors of many species' starships and a key system of faster-than-light warp drives. The related element (isotope?) Trilithium has various uses as a weapon. |
| Illudium Phosdex | Looney Tunes | Also known as the shaving cream atom, it was found only on Planet X, which was unfortunately destroyed when both Duck Dodgers and Marvin the Martian tried to conquer it for Earth and Mars. |
| Illudium Q-36 | Looney Tunes | Used by Marvin the Martian as a planet-destroying explosive. |
| Jumbonium | Futurama | Each atom of this element is large enough to be easily visible to the naked eye, with marble-sized nucleons and electrons. |
| Kryptonite | DC Comics | Usually a green crystal, sometimes other colours. Most Kryptonite was created during the destruction of Superman's home planet Krypton; exposure to it is highly detrimental to Kryptonians (prolonged exposure can also harm Earth-humans). Can be used as a power source or ornament, but is more frequently used as a weapon against Kryptonians. |
| Mithril | Middle-earth, several video games and role-playing games | A light, silvery metal that is as strong as steel, but very light and easy to work. While mithril has properties similar to those of titanium or aluminium alloy, the fact that it was mined in native form in Moria suggests it has no direct real-world analogue. It is used for making superb chain-mail armour and other means of protection. An alternate spelling, "Mythril", appears in the video game series Final Fantasy with basically the same properties as Mithril. |
| Narrativium | The Science of Discworld and The Science of Discworld II: The Globe | An element unique to the Discworld; proto-substance from which all things spring forth. It is the fundemental element of Story, and is how things know what they're meant to be. |
| Octiron | Discworld | A dense black metal that is a large part of the Discworld's crust. It is highly magical with a melting point above the range of metal forges. The gates of Unseen University are made out of it. A needle made of octiron will always point to the Hub, the centre of the Discworld's magical field; it will also darn its owner's socks by itself. The University tower bell ("Old Tom" is made of it, and rings audible silences. Coin's staff in Sourcery was made out of it. |
| Omega | Star Trek: Voyager | Most powerful and dangerous element known in the Federation. Omega can consist of one molecule, or as a cluster of many. The more there are, the more danger it represents. An Omega molecule was created by scientists on a base in the Lantaru Sector. Omega destabilized and exploded, destroying the base and subspace in the whole sector. Information about Omega is limited to Starfleet Captains and Flag Officers. If Omega is detected, the Omega Directive is implemented and Starfleet is contacted to dispatch a force to deal with the molecule/s. Omega can be synthesized from Boronite Ore. |
| Orichalcum | Mythology (Atlantis) | A reddish metal mined in Atlantis, used to make structures and walls. May be based on an actual mineral or gold/copper alloy, possibly Auricupride. |
| Phostlite | Tintin, "The Shooting Star" | Discovered by Professor Decimus Phostle. |
| Thyrium | Matthew Reilly's Temple | This element came from a meteor and was used in a doomsday bomb. |
| Unknown Element from The Colour out of Space | H. P. Lovecraft's horror tale "The Colour out of Space" | First identified in a meteorite that lands in a farmer's field, it has a distinctive, unnatural colour not found in nature. An alkaline metal, it is highly toxic and somewhat mutagenic. |
| Unobtainium | The Core, many thought experiments | Unobtainium is really any a material that is unobtainable (for example titanium was called unobtainium during the 60s within American aerospace due to the Soviets cornering the market); although it can be that it possesses properties that are unlikely or impossible for any real material to possess and is hence completely unobtainable. It is also an informal name for an improbably strong material found in works of science fiction, only used explicitly in The Core. It is typically used to fill a plot hole, allowing characters to do things that may not be physically possible even in principle; although a possibly more correct term is "handwavium". |
| Upsidaisium | The Rocky and Bullwinkle Show | Upsidasium is a metal that is lighter than air and can be obtained by mining in upsidasium-rich areas. |
| Vibranium | Marvel Comics | An extraterrestrial metal that exists in two forms. Wakandan vibranium absorbs vibrational energy (e.g. sound). The more energy it stores the tougher it becomes, due to the energy reinforcing its molecular bonds. If the bonds are broken, all the energy is released, causing an explosion. It is found only in the African nation of Wakanda, ruled by the Black Panther. The other form, Antarctic vibranium, emits a vibration that separates the bonds of other metals, liquifying them. |
| Vik-ro | Carson of Venus by Edgar Rice Burroughs | One of the two components of Lor (see below) which when combined with Yor-san results in total annihilation of the Lor, releasing tremendous energy. |
| Yor-san | Carson of Venus by Edgar Rice Burroughs | One of the two components of Lor (see below) which when combined with Vik-ro results in total annihilation of the Lor, releasing tremendous energy. |
| Name | Isotope of | Source | Uses |
|---|---|---|---|
| Quadium | Hydrogen | The Mouse that Roared | Common hydrogen has one proton, one electron, and no neutrons. Deuterium and Tritium have, respectively, one and two neutrons per atom, and are used for hydrogen bombs. Quadium, following logic, must have three neutrons, and is, in the story, capable of blasting an entire continent off the face of the Earth. |
| Plutonium-186 | Plutonium | The Gods Themselves | An isotope of plutonium which is too unstable to exist in our universe but which exists naturally in parallel universes whose strong nuclear forces are more intense. |
| Name | Source | Uses |
|---|---|---|
| Aluminum | Star Trek | Transparent metal used for enclosing whale tanks (not entirely inaccurate now with the development of transparent alumina) |
| Cermet | Final Fantasy XI | Super-hard material used to build structures, armor and weapons. |
| Gold | Various RPGs | Used to make weapons and armor, often superior in strength to bronze or silver, despite gold's high malleability. |
| Iron | Discworld, The Boggart, et cetera. | Is completely and totally immune to magic, in much the same way as lead is resistant to radiation. In many fantasy novels, iron is deadly to elves and/or fairies. |
| Neutronium | Star Trek, et cetera. | An extremely dense material made entirely of neutrons, it is theorized to be the main constituent of neutron stars. It is actually expected to decompose messily at any reasonable pressure, but this doesn't prevent authors from building space ships out of it and attributing to it various desirable qualities as armor, structural material, etc. |
| Silver | German folklore, et cetera. | Is proof against werewolves, which are immune or resistant to normal weapons. Used in form of blade or bullet, which led to the idiom silver bullet |
| Tin foil | Various conspiracy theorists, Signs | Supposedly, one can protect oneself against governmental/alien mind-control rays by wearing a tinfoil hat. |
| Ununpentium (a.k.a. Elerium-115) | Urban myths, UFO conspiracy theory culture, Dark Reign, The Core | This material, as-yet unsynthesized in laboratories but given a slot on the periodic table, has all sorts of lore around it, as |
| Name | Source | Uses |
|---|---|---|
| Adamant | Diamond | a stone of impenetrable hardness. |
| Agatean Thunder Clay | The Last Hero, Discworld | A powerful explosive, triggered by reacting with acid. The explosion also cancels out magic, possibly with the thaumatological equivilent of an electromagnetic pulse. |
| Anti-Ice | Stephen Baxter | A form of antimatter, stable due to its superconductive properties, that releases vast quantities of energy when heated. |
| Archerite | Star Trek: Enterprise | A compound "invented" by Shran. Whilst pursuing the Xindi he claimed he was searching for the rare compound "Archerite". |
| Arenak | E. E. Smith's Skylark of Space series | A fictitious transparent metal 500 times stronger and harder than the strongest and hardest steel, and is used primarily for spaceship armor. It is created by molding a plastic-like clay called the "matrix" into the desired shape, then coating the matrix in a weak saline solution and running an electric current across it. Pigments may be incorporated into the matrix to make opaque colored arenak. |
| Balonium | ||
| Biphase carbide | Ogre game | Conceived by Steve Jackson as fighting vehicle armor in the Ogre game |
| Blackrock | Ultima series | A mystical mineral that can bend space and time, and is known to resist magic. It is able to open portals to other dimensions and summon creatures through them, and it is crucial to producing the Black Moongate, by which the Guardian attempted to enter Britannia. It was also how the Avatar managed to escape the Guardian's trap on the world of Pagan (and became the Titan of Ether) and how he contained the Armageddon spell by which he ascends and the Guardian is destroyed. Blackrock is used in Ultima IX to make strong armor and a Blackrock sword, though its suitability for this purpose has never previously been established. |
| Black Smoke | The War of the Worlds | Toxic gas used by Martian invaders. Spectrographic analysis shows an unusual triplet of blue lines. |
| Carbonite | Star Wars | Han Solo is frozen in a block of this and successfully revived later. Not to be confused with the real explosive material carbonite |
| Cheddite | Star Smashers of the Galaxy Rangers | Made by irradiating Cheddar cheese, it enabled faster-than-light travel. Not to be confused with the real class of explosive materials cheddites |
| Chemical X | The Powerpuff Girls | A mysterious chemical created by Professor Utonium. When he accidentally mixed it with sugar, spice, and everything nice, it created The Powerpuff Girls. |
| Cinnabryl | Mystara Dungeons & Dragons setting | A glowing red magical metal that temporarily halts the Red Curse created by vermeil (see below). Depleted cinnabryl is called red steel, and is used for weaponry and armour. Not to be confused with the real mercury ore cinnabar. |
| Corbomite | Star Trek episode The Corbomite Maneuver | A meta-fictional substance that was "invented" by Captain Kirk as a way to bluff his way out of a dangerous situation in which a vastly superior alien vessel was threatening to destroy the ship. Kirk claimed that a Corbomite-based weapon, which the Enterprise supposedly carried as a last-resort deterrent, was capable of returning an attacker's destructive energy to the attacker, resulting in a huge explosion which would wreak horrendous devastation through a large region of space. |
| Dagal | E. E. Smith's Skylark of Space series | conceived by E. E. Smith for ship armor in the Skylark of Space series |
| Dargonite | Marvel Comics | possibly the same as uru. |
| Darksteel | Magic: The Gathering storylines | A type of metal that is, for all intents and purposes, indestructible. Used in various robots, machines, artifacts, and equipment. |
| Dilithium | Star Trek | Crystalline substance used in warp engines |
| Duranium | Star Trek | construction materials in the Star Trek universe |
| Dureum | E. E. Smith's Lensman series | |
| Flowstone | Magic: The Gathering storylines | A type of stone which can be commanded or molded into an endless number of shapes, or animated. It is composed of millions of microscopic nanorobots. |
| Gekiganium | Martian Successor Nadesico | In the Martian Successor Nadesico anime series, the main characters often watch another (fictional) anime series caclled Gekigangar III. This series-within-a-series features robots built out of a supposedly indestructible alloy referred to as Gekiganium. |
| GND | Gundam Wing | Genetic on Universal Neutrally Different Alloy. a.k.a. Gundanium (not to be confused with Gundarium, a.k.a. Lunar Titanium of Universal Century Gundam. Created in high temperature plasma only formed in zero gravity, with molecular scale refinements only possible in gravitionally stable Lagrange Points. Electrically neutral and almost entirely resistant to change, it is used in the manufacture of special beam weapons and armor. Expensive cost to manufacture makes prohibts general military use. |
| Hagane | Vagrant Story | An alloy made by combining iron and bronze. Used to make both weapons and armour. (Hagane is Japanese for "steel.") |
| Herculite | USOS Seaview | conceived by Theodore Sturgeon for the windows of USOS Seaview |
| Hudderite | Paul Preuss's novel The Core | A compound able to scratch diamond and solid under extreme temperatures and pressures. Used as drill components to drill into unprecedented depths and horizontal distances. Composed of carbon, beryllium and silicon. |
| Ice-Nine | Cat's Cradle | Has a melting point of 114 degrees Fahrenheit, and turns all water it comes into contact with into ice-nine. Not related to the real-world ice-IX. |
| Imipolex G | Gravity's Rainbow | A plastic invented by German chemist Laszlo Jamf and used in post-WWII rocketry. Cross-links among its chemical chains can be controllably formed and re-broken, making it the world's first erectile polymer. |
| Inoson | E. E. Smith's Skylark of Space series | conceived by E. E. Smith for ship armor in the Skylark of Space series |
| Latinum | Star Trek | A liquid which cannot be replicated or synthesized. Used as a dominant form of currency by the Ferengi. As it is difficult to properly measure liquid for currency transactions, premeasured amounts of latinum are inserted into hollow cores of gold bullion of various sizes, leading to the standard units: slip, strip, bar and brick. For an exposition on the future of money and how latinum might come to be, see "Proposal for an Ideal Nano-Specie: Gold-Pressed Latinum" by Robert Freitas . |
| Lor | Carson of Venus by Edgar Rice Burroughs | A tremendously energy-dense airship propellant.
"Fuel for the life of the ship was aboard; and it took up very little space, for it could all be held in the palm of one hand." Lor "contains an element called yor-san (see above), as yet unknown to Earth men, and another element, vik-ro (see above), the action of which upon yor-san results in absolute annihilation of the lor," thus yielding tremendous energy as compared to a mere chemical reaction. |
| Lunar Titanium | Universal Century Gundam | a.k.a. Gundarium, because of its use in the famed RX-78 Gundam mobile suit. Virtually impenetrable from 120mm tank cannon ammunition, is erosion and weather proof, and has some degree of resistance from energy weapons. Manufactured in zero gravity, and, despite its name, is not made on the moon, but originally from the Earth Federation's asteroid base, Luna 2. |
| Magestone | Mage Knight | Crystalline substance coveted by the Atlantean Empire for technomagical experiments. Causes mutations with prolonged exposure; mutants are known as Mage Spawn. |
| Kemocite | Star Trek: Enterprise | A multi-phasic isotope that has many applications, depending on the level of refinement. Kemocite was one of the key components in the Xindi weapon and was produced by a Xindi-Sloth plant led by Gralik. |
| Naquadah | Stargate SG-1 | The Goa'uld power source |
| Naquadria | Stargate SG-1 | A highly unstable variant of naquadah with greater explosive properties. It can also be used for the powering of hyperspace engines. Naquadria is formed from naquada in an artificial chain reaction. The only known planet containing naquadria is Langara where large deposits were created millenia ago by an unknown Goa'uld scientist. Unprotected exposure can lead to brain damage, delusions and/or schizophrenia. |
| Nth Metal or Ninth Metal | DC Comics | the alien anti-gravity substance that allows Hawkman to fly. |
| Plasteel | The Dune books | Hard yet moldable; used frequently as armor. |
| Plasphalt | The Muller-Fokker Effect | Paving material. |
| Polydichloric Euthimal (PDE) | Terminator 2 | Used here as a high explosive. |
| Porkanium Alloy | The Muppet Show | The material the SS Swine Trek is made of in Pigs In Space. Parody of Tritanium. |
| Rearden Metal | Ayn Rand's Atlas Shrugged | |
| Scrith | The Ringworld novels | Conceived by Larry Niven for the base structure of the Ringworld |
| Smilex | Batman | Poison created by The Joker, kills within minutes, leaves victims with a rictus grin on their faces |
| Thiotimoline | Isaac Asimov | Conceived and described in a spoof scientific paper entitled The Endochronic Properties of Resublimated Thiotimoline in 1948. Thiotimoline has the property of dissolving in water slightly before the actual contact with water. |
| Tiberium | Command and Conquer | Highly valuable crystal in the Command and Conquer series, Usually green, sometimes blue. Extremely toxic and mutagenic to terrestrial life-forms. Tiberium is used as a resource for mining. |
| Transparisteel | Star Wars Expanded Universe. | A completely transparent metal at least as strong as steel. Used primarily for ship windows. |
| Transparent aluminum | Star Trek | Same physical properties as aluminum, but is completely transparent. A real alumina (i.e., aluminum oxide) exists, known as transparent alumina. |
| Trellium-D | Star Trek | used for insulation against gravitic distortions by the Xindi, Starfleet, and others. Causes brain damage in Vulcans. |
| Trillite | see Yakka | |
| Trinium | Stargate SG-1 | Very brittle in raw form but can be refined into a substance 100 times stronger & lighter than steel. Stargate Command has attempted to acquire reserves of it several times. |
| Trioxyn gas | Return of the Living Dead series | Gas that brings the dead back to life as zombies |
| Tritanium | Star Trek | construction materials in the Star Trek universe |
| Uru | Marvel Comics | an Asgardian material. Thor's hammer is made of this. |
| Vermeil | Mystara Dungeons & Dragons setting | a magical red dust covering the Savage Coast area of Mystara. It causes a sickness similar to radiation poisioning, called the Red Curse. |
| Vespene Gas | Starcraft | a valuable natural gas, especially used to manufacture buildings and flying units. |
| Vibranium | Marvel Universe | a sound-absorbing metal |
| Voidstone | Dungeons and Dragons | a material from the Negative Energy Plane |
| Yakka | Marvel Comics | a sound-sensitive metal (sometimes called a mineral). Also known as "Trillite." |
| Ziff | Book of Mormon | An unknown metal mentioned in the Book of Mormon (Mosiah 11:3). In Hebrew, this term means brightness, i.e. metallic brightness. It is possibly a mistranslation of zinc. Other have speculated that this refers to Orichalcum, providing a link with Atlantis. |
| Name | Source | Uses & effects | |
|---|---|---|---|
| Accela | Serial Experiments Lain | Accela is a nano-bot drug that increases the processing power of the brain, and makes its user feel that time has slowed down, i.e. that they are "accelerated". | |
| Altruizine | Stanislaw Lem's Altruizine; or, a True Account of How Bonhomius the Hermitic Hermit Tried to Bring About Universal Happiness and What Came of It | A drug which causes the user to feel emotions, pain sensations, etc. of other people in proximity. Invented to promote altruism. | |
| Ambrosia | Deus Ex | Ambrosia is a temporary "cure" for the disease 'the Grey Death'. It is really a large number of microscopic pods in a liquid suspension. The pods attach to the nanobots for a while and disable them, temporarily shutting down the nanobot-induced(and eventually-fatal) autoimmune response. | |
| Blinkmoth Serum | Magic: the Gathering | Blinkmoth serum is created by killing and harvesting blinkmoths. It grants the user extreme intelligence, self-awareness, and understanding. It is extremely addictive. | |
| Buffout | Fallout | Strength enhancer | |
| Cake | Brass Eye | "Remember, Cake is a 'made up' drug!" | |
| Comatonin | Futurama | fast acting tranquilizer | |
| Cordrazine | Star Trek: The Next Generation | Powerful stimulant used to revive patients in an emergency, such as cardiac arrest. 25 mL is usually a lethal dose to humanoids, causing hallucinations, madness and death. | |
| Dimoxinil | The Simpsons | Hair regrowth drug. Requires daily application or regrown hair is lost. | |
| Drencrom | A Clockwork Orange | Ingredient in milk-plus, sold in the Korova Milkbar. Likely a reference to adrenochrome. | |
| Dried Frog Pills | Discworld | A hallucinogen, used by the Bursar of Unseen University. The pills are carefully designed to make him hallucinate that he is sane. | |
| Dyne | City of Heroes | An addictive narcotic that is peddled by more than one street gang. A stronger version, Superadyne, will provide pain immunity and induce the user with violent tendencies. Overuse of Superadyne will degenerate a user into a Troll, which makes them brainless but gives them superhuman powers. | |
| Ephemerol | Scanners | Tranquilizer, used as a morning sickness remedy. Produces mutations during development. | |
| Excelsior | City of Heroes | A powerful narcotic that raises the normal physical attributes of a human, including an incredibly high pain tolerance. The street gang known as the Freakshow take advantage of the pain tolerance to replace their limbs with cybernetic implants. | |
| Felicium | Star Trek | Narcotic | |
| Focusin | The Simpsons | A Ritalin-like drug | |
| Flash | Andromeda (TV series) | A highly addictive drug designed for better slipstream navigation. | |
| Formula 51 | Formula 51 | Narcotic | |
| Gleemonex | Brain Candy | Anti-depressant | |
| Happy Plant | Dinosaurs (television) | Euphoria | |
| Haza | Supernova | ||
| Iocaine Powder | The Princess Bride by William Goldman | A deadly poison. Has no odor or taste. Dissolves instantly in liquid. It is possible to build an immunity to the poison over the course of several years. Used by the hero Wesley to outsmart the Sicilian, Vizzini. | |
| Jet | Fallout | Euphoric, highly addictive. Plays important role in world of Fallout II. | |
| Jumpstart | Transmetropolitan | An amphetamine-like stimulant, taken orally in pills or smoked. Used to dilute space dust, it is known to cause constipation. | |
| Ketracel white | Star Trek | a white, liquid drug to which genetically engineered Jem'Hadar super-soldiers are born addicted. The drug is supplied to the Jem'Hadar by the Vorta, the middle-men of the villainous Dominion. All Jem'Hadar soldiers are supplied with a device that pumps the drug through a transparent tube into their system from a small capsule. Without the drug, Jem'Hadar soldiers experience painful withdrawal symptoms and eventually death. The drug serves the Jem'Hadar as a form of nutrition, and their genetic structure is designed to be dependent on its presence, in order to prevent rebellion against the Dominion. Only one case of a non-addicted Jem'Hadar soldier is known: an anomaly which was the result of a random genetic mutation. Some sources have also indicated that the drug can be used as a narcotic by other species. | |
| KR-3 | Flow My Tears, The Policeman Said | An experimental compound which disrupts the brain's ability to distinguish alternate realities. Even if they do not consume the drug, people involved in the drug user's life can be shifted into an alternate existence based on the drug user's mind. | |
| Levitol | Mallworld | A controlled but largely legal recreational drug which enables the consumer to fly. | |
| Lot 6 | Firestarter | Hallucinogen; telekenetic power enabler | |
| Lotus | Homer's Odyssey | A plant, possibly native to Libya, with opium-like sedative properties. | |
| Mañanacillin | American Flagg! | Combination antibotic and contraceptive, heavily classified studies show long term use leads to sterility. | |
| Magic Potion | Asterix | Gives the imbiber temporary super-strength. Apparently has permanent effects if one falls into an entire cauldron in childhood. | |
| Mechanics | Transmetropolitan | Recreational drug taken with the aid of an AI. Both the AI and the human user enjoy hallucinations; the drug causes portions of the human body to develop into cybernetic implants. | |
| Melange | Dune series | Also called Spice. Mind altering; whites of eyes turn blue as a side-effect. Makes space travel possible. | |
| Mentats | Fallout | Intelligence booster. Note reference to Dune. | |
| Neuroin | Minority Report | Effects similar to heroin, administered intraveneously. | |
| Panadote | The Dying Sun | Painkiller | |
| Polydichloric Euthimal (PDE) | Outland | Used here as an amphetamine compound. | |
| Project 5 formulas | The Lawnmower Man | A collection of drugs designed to increase neurochemical activity and enhance intelligence. Developed and tested on animals, their use on humans is strongly contraindicated. | |
| Prozium | Equilibrium | A drug in liquid form that is injected directly into the neck. It is an emotion suppressor, and a user will not feel unhappiness, depression or anger, as well as all positive emotions. The effect is temporary, and Prozium must be taken at regular intervals or the user will start to feel again. Prozium is collected at a distribution center called Equilibrium. | |
| Redeye | Cowboy Bebop episode 1 | Amphetamine-type recreational drug, highly illegal and extremely valuable. Users perceive a slowed rate of time, and seem to have incredibly quick reflexes. | |
| Repressitol | The Simpsons | Supresses unpleasant memories. | |
| Serum 114 | A Clockwork Orange | Injected during the Ludovico treatment, which uses a series of violent images forced on the viewer in order to cure violent urges in criminals. (Stanley Kubrick often used the number 114 in his films; compare the CRM-114 encryption device in Dr. Strangelove.) | |
| Silver Serpent Venom | Ultima | Dramatic increase in strength, poisonous. | |
| Slab | Discworld | 'Recreational' (for trolls). Technically not a fictional drug, so much as one that has no intoxicating effect on humans as Discworld trolls are silicon based lifeforms. Slab is described as being a mixture of chloric ammonium and radium. | |
| Slappers | Batman Beyond | A steroid, absorbed through the skin. Based on Venom (see below). | |
| Sleep-EX | Rat Race | Fights insomnia; in large doses it can cause unconsciousness in fully awake people. | |
| Soma | Brave New World | An antidepressant which is hallucinogenic if taken in sufficient quantities; developed under governmental subsidies and engineered to have almost no side effects. Large doses cause death by depressing the medulla oblongata's respiration centers. (Reference to soma of the Vedic lore, which is the elixir of immortality.) | |
| Somnambutol | American Flagg! | Hallucinogenic barbituate, used for both recreational use, in small doses, and riot control, where it is commonly used in Snowball 99 capsule bullets. | |
| Space | Transmetropolitan | Hallucinogen, often taken in the smokeable form space dust. | |
| Spaceoline | Isaac Asimov's "I'm in Marsport Without Hilda" | Medication given to prevent space sickness during interplanetary travel. Users babble, speaking in free association; the ability to react to stimuli (including sexual arousal) is reduced. The legal version is in common use, but slight chemical alterations can transform it into a hazardous narcotic. | |
| Spank | Grand Theft Auto III | Narcotic | |
| Spark | G.I. Joe | Erratic behavior. Lethal in excessive doses. | |
| Spice | Star Wars | Mind-altering. Varities include ryll and the strongest, glitterstim. | |
| Stimutacs | Sealab 2021 | "Herbal dietary supplement", produced from all natural ingredients (99% kelp, 1% | |
| Substance D | A Scanner Darkly | Dampens the links between the left and right hemispheres of the brain, causing vivid hallucinations. Also called "Death," it is lethally addictive. | |
| Synthemesc | A Clockwork Orange | Ingredient in milk-plus, sold in the Korova Milkbar. Synthemesc is a hallucinogen, its name derived from "synthetic mescaline". | |
| Trinity | The Crow: City of Angels | ||
| Tripwire | Transmetropolitan | Hallucinogen simulator, used and abused by sentient AIs. | |
| Valkyr | Max Payne | Highly addictive narcotic, that spread rapidly through New York City. Junkies are driven mad and go on insane killing sprees. | |
| Vellocet | A Clockwork Orange | Ingredient in milk-plus, sold in the Korova Milkbar. Produces alertness and ultra-violent tendencies. | |
| Velocity-9 and Velocity-10 | The Flash comics | Addictive drug that gives the user super-speed, created by the supervillain Vandal Savage. | |
| Venus Drug | Star Trek | Aphrodisiac | |
| Venom | Batman | Highly addictive super-steroid. Increases physical performance and stamina. | |
| Vraxoin | Doctor Who | Addictive and deadly drug created from Mandrells, alien monsters from the planet Eden. | |
| Yakov's Elixir | The Inspector General | Snake oil | |
| Zyme | Deus Ex | Pleasure inducing drug. Small doses can be quite lethal. |
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