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The United States Code of Federal Regulations (CFR) is the codification of the general and permanent rules published in the Federal Register by the executive departments and agencies of the Federal Government.
Rules will be entered into the CFR as a result of the United States Congress passing laws which need to be administered by one or more federal executive departments and agencies. Additionally, the federal non-Congressional entities involved in administering the law or laws in question can create administrative law, to the extent reasonably allowed by Congress, to effectively carry out the legislation. Such administrative law will also go into the CFR.
For example, if Congress passed a law that simply stated that there are not to be "excessive" levels of mercury in any significant body of water in the United States (but defined things no further), an entity designated, as part of the law, to enforce it (probably the United States Environmental Protection Agency) could define in a scientific way what an excessive level of mercury is, as well as what constitutes a significant body of water. The Agency's definitions, and its plan of enforcement for what Congress intended (along with listed penalties for violation coming from Congres unless Congress specified otherwise) will all go into the CFR.
Also, enabling legislation can be passed by Congress which gives a federal non-Congressional entity wide latitude in creating rules. For example, the United States Environmental Protection Agency could be designated by Congress to pass rules "that control harmful pollutants"; the Agency could then pass broad rules (including definitions and enforcement provisions), in the absence of existing specific laws, to control lead emmissions, radon emissions, pesticide emissions, and so forth. Such rules, including any Congressional- or Agency-created definitions and enforcement provisions, will all go into the CFR.
The CFR is a multi-volume set divided into 50 titles that represent broad areas subject to Federal regulation. Each volume of the CFR is updated once each calendar year and is issued on a quarterly basis.
List of regulation Titles: