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Ayahuasca is an entheogenic drink prepared from segments of the vine Banisteriopsis caapi. Sections of vine are boiled with leaves from any of a large number of other plants (such as Psychotria viridis or Diplopterys cabrerana) yielding a brew containing the powerful hallucinogenic alkaloid N,N-dimethyltryptamine, combined with an MAOI, such as harmaline, harmine, Brazil, where it has religious use
Nowadays, the term ayahuasca also means analogous concoctions made with other plants that contain the two main components, an MAOI and a DMT. The DMT is the main "active ingredient", causing the desired effects. The MAOI is necessary for DMT to be taken orally. However some actual shamans object to this and state that the Banisteriopsis vine is the only defining ingredient, everything else being of secondary importance.
Some plant sources of MAOI:
In Brazil there are a number of religious movements based on the use of Ayahuasca, usually in a animistic context that may be Shamanistic or, more often, mixed with Christian imagery.