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Agonist



         


An agonist is a substance that binds to a receptor and triggers a response by the cell. An agonist is the opposite of an antagonist in the sense that while an antagonist also binds to the receptor, it fails to activate the receptor. A partial agonist activates a receptor but does not cause as much of a physiological change as does a full agonist. The receptors of the human body work by being stimulated or inhibited by natural (such as hormones and neurotransmitters) or synthetic (such as drugs) agonists and antagonists.

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Etymology

Stems from the Late Latin word agnista, 'contender', from the Greek agnists, 'contestant', from agn, 'contest'. An agonist is a chemical contestant or contender.





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