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He made use of his love of music and of the opera in particular in at least two of his novels, Serenade (about an American opera singer who loses his voice and who, after spending part of his life south of the border, re-enters the States illegally with a Mexican prostitute in tow) and Mildred Pierce (where, as part of the subplot, the only daughter of a successful businesswoman trains as a singer).
Critics have pointed out that there is a basic formula pervading most of Caine's fiction. Almost always, with the notable exception of Mildred Pierce, a man falls for a woman -- the femme fatale (see also stock character) -- becomes involved in criminal activity with the woman, and is eventually betrayed by her. Invariably, Caine's novels are about sex, crime and violence.
Cain continued writing up to his death. However, the many novels he published from the late 1940s onward never rivalled his earlier successes. He died an alcoholic, aged 85.